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分娩期间母体液体过载;足月婴儿的经胎盘低钠血症及短暂性新生儿呼吸急促风险

Maternal fluid overload during labour; transplacental hyponatraemia and risk of transient neonatal tachypnoea in term infants.

作者信息

Singhi S C, Chookang E

出版信息

Arch Dis Child. 1984 Dec;59(12):1155-8. doi: 10.1136/adc.59.12.1155.

Abstract

Cord serum sodium concentrations in two groups of vaginally delivered, singleton term infants were correlated with the incidence of transient neonatal tachypnoea. Hyponatraemia (cord serum sodium less than 130 mmol/l) was seen in 71 of 180 (39%) infants born to mothers who received an intravenous infusion of aqueous glucose solution during labour (study group) compared with 6 of 103 (6%) infants born to mothers who did not receive any intravenous fluid treatment (controls). The incidence of transient neonatal tachypnoea was 4.5 times higher for hyponatraemic infants in the study group (11 of 71) than for normonatraemic infants in the same group (3 of 109) and the control group (3 of 97). The difference was not attributable to other perinatal or neonatal characteristics. Our findings suggest an increased risk of transient neonatal tachypnoea in term infants who suffer from transplacental hyponatraemia after their mothers received intrapartum infusion of aqueous glucose solutions.

摘要

两组经阴道分娩的足月单胎婴儿的脐血血清钠浓度与新生儿短暂性呼吸急促的发生率相关。在分娩期间接受静脉输注葡萄糖水溶液的母亲所生的180例婴儿中,有71例(39%)出现低钠血症(脐血血清钠低于130 mmol/L)(研究组),而未接受任何静脉输液治疗的母亲所生的103例婴儿中有6例(6%)出现低钠血症(对照组)。研究组中低钠血症婴儿发生新生儿短暂性呼吸急促的发生率(71例中有11例)是同一组中正常钠血症婴儿(109例中有3例)和对照组(97例中有3例)的4.5倍。这种差异并非归因于其他围产期或新生儿特征。我们的研究结果表明,母亲在分娩期接受葡萄糖水溶液输注后,患有经胎盘低钠血症的足月婴儿发生新生儿短暂性呼吸急促的风险增加。

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