Mansani F E, Caltabiano M, Gazza F
Biol Res Pregnancy Perinatol. 1984;5(4):153-6.
This study relates an incidence of maternal and feto-neonatal side effects at the Institute of Obstetrics and Gynecology of the University of Parma. Neonatal morbidity and mortality upon administration of corticosteroids and beta-mimetic drugs were observed. Remarkable was the low rate of maternal side effects and that their seriousness was quite inferior to that found by other authors. The fetal and neonatal side effects or symptoms were very few and it was impossible to ascertain whether they were due to the therapy, a consequence of maternal pathological events, the kind of delivery, gestational age or some other unknown factor. Finally, this study points out that the maternal, fetal and neonatal side effects can not be considered serious enough to judge the associated tocolytic and corticosteroid treatment unacceptable.
本研究阐述了帕尔马大学妇产科研究所孕产妇及胎儿-新生儿副作用的发生率。观察了使用皮质类固醇和β-拟交感神经药物时的新生儿发病率和死亡率。值得注意的是，孕产妇副作用发生率较低，且其严重程度明显低于其他作者的发现。胎儿和新生儿的副作用或症状极少，无法确定它们是由治疗引起的，还是孕产妇病理事件、分娩方式、孕周或其他未知因素导致的。最后，本研究指出，孕产妇、胎儿和新生儿的副作用并不严重，不足以判定相关的宫缩抑制剂和皮质类固醇治疗不可接受。
