Forni E, Borri A M, Zadra F, Lo Monaco G, Bordoni P, Clerico D
Chir Ital. 1984 Aug;36(4):603-19.
In a total of 142 patients with adenocarcinoma of the proximal third of the stomach and cardia, curative resection was carried out in 88 during the period 1960-1980. The patients were divided in two groups. I group included 32 patients with tumor distal to the esophagogastric junction. In II group (54 patients) the tumor involved the esophagogastric junction (adenocarcinoma of the gastric cardia). In I group, when the proximal border of the cancer was well defined and sufficient length was maintained between the proximal tumor border and esophagogastric junction, the abdominal approach was preferred and the operation performed was generally a total gastrectomy combined with splenectomy and celiac node dissection. Distal pancreatectomy was performed as necessary. In most patients of the II group, the operation was performed using separate abdominal and right-sided thoracic incisions. Two principally types of operation were used: extended total gastrectomy and extended proximal subtotal gastrectomy, depending on degree of gastric wall involvement, combined with extensive esophagectomy, splenectomy and regional nodes dissection in both cases. Distal pancreatectomy was not performed routinely but only as necessary. In this group of patients there was no significant difference in the overall cure rate between the extended total gastrectomy and the extended proximal subtotal gastrectomy. Operative morbidity and mortality rates were also comparable.
在总共142例胃近端三分之一和贲门腺癌患者中,1960年至1980年期间88例行根治性切除术。患者分为两组。I组包括32例肿瘤位于食管胃交界远端的患者。II组(54例患者)肿瘤累及食管胃交界(胃贲门腺癌)。在I组中,当癌的近端边界明确且近端肿瘤边界与食管胃交界之间保持足够长度时,首选经腹入路,通常施行全胃切除术联合脾切除术及腹腔淋巴结清扫术。必要时行远端胰腺切除术。II组大多数患者采用腹部和右侧胸部单独切口进行手术。根据胃壁受累程度,主要采用两种手术方式:扩大全胃切除术和扩大近端胃次全切除术,两种情况均联合广泛食管切除术、脾切除术及区域淋巴结清扫术。远端胰腺切除术并非常规施行,仅在必要时进行。在这组患者中,扩大全胃切除术和扩大近端胃次全切除术的总体治愈率无显著差异。手术 morbidity 和死亡率也相当。 (注:“morbidity”此处结合语境推测可能是指手术并发症发生率之类的意思,但原文未明确给出准确释义)