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[人体正常胃黏膜表面细胞及腺颈部区域细胞的电子显微镜研究]

[Electron microscopy studies of surface cells and cells in the area of the glandular neck of normal stomach mucosa in humans].

作者信息

Belák M, Lakata E, Hildebrand T

出版信息

Dtsch Z Verdau Stoffwechselkr. 1984;44(6):261-5.

PMID:6525968
Abstract

The authors describe the submicroscopical structure of surface epithelial cells of the mucosa and cells of the stomach gland cervix in men. On the basis of electronmicroscopic studies of bioptic samples of the stomach mucosa the surface epithelium of the stomach mucosa in men was found to be covered with high cylindrical cells showing typical small, relatively low microvilli at the luminal side with numerous mucous granules in the supranuclear zone of the cells. The basal part of the cell is extremely dense containing numerous ribosomes, a Golgi apparatus and mitochondriae. Isthmic cells were found to differ from surface cells by the location of the nucleus and the amount of mucous granules, which are larger and granular in the rule. The cells of this zone are mutually connected by desmosomes. The granular endoplasmic reticulum is present at a relatively lesser amount as compared to the former group of cells. These cervical cells are of importance from the viewpoint of regeneration and may differentiate into the other cell types of the stomach mucosa.

摘要

作者描述了男性胃黏膜表面上皮细胞和胃腺颈部细胞的亚微观结构。基于对胃黏膜活检样本的电子显微镜研究,发现男性胃黏膜的表面上皮覆盖着高柱状细胞,这些细胞在管腔侧呈现典型的小而相对较低的微绒毛,在细胞核上方区域有大量黏液颗粒。细胞基部极其致密,含有大量核糖体、一个高尔基体和线粒体。峡部细胞在细胞核位置和黏液颗粒数量上与表面细胞不同,黏液颗粒通常更大且呈颗粒状。该区域的细胞通过桥粒相互连接。与前一组细胞相比,粗面内质网的数量相对较少。从再生的角度来看,这些颈部细胞很重要,并且可能分化为胃黏膜的其他细胞类型。

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