Godlewski G, Rouy S, Gay G, Bureau J P, Eledjam J J
J Chir (Paris). 1984 Nov;121(11):667-72.
Liver resection is performed in 15 pigs by means of low divergent Nd YAG laser, the hepatic pedicle being clamped and not. Clamping does not modify the efficiency of laser hemostasis during resection but increases the thickness of the ischemic layer underlying the cut liver edge. The coagulation necrosis and the edematous layer are more thickened. Migration of inflammatory cells and young fibrosis present at day 3 are gaining ground until day 15. During the same period, biliary neoductules and nodules of hepatic regeneration appear. Hepatic inflow being conserved, these reactions are delayed and less intensive. The hyperthermia, the inflammatory cellular reaction and the deepness of parenchymal damages induces by pedicle clamping are suitable for antitumoral surgery. Cooling effects of hepatic inflow are better for traumatic surgery.
通过低发散钕钇铝石榴石激光对15头猪进行肝切除术，肝蒂是否钳夹。钳夹并不改变切除过程中激光止血的效率，但会增加肝切缘下方缺血层的厚度。凝血坏死和水肿层增厚更明显。第3天出现的炎性细胞迁移和早期纤维化在第15天前不断进展。同期，出现胆小管新生和肝再生结节。保留肝血流时，这些反应延迟且程度较轻。肝蒂钳夹引起的高热、炎性细胞反应和实质损伤深度适用于肿瘤手术。肝血流的降温作用对创伤手术更有利。
