Godlewski G, Rouy S, Gay G, Bureau J P, Eledjam J J
J Chir (Paris). 1984 Nov;121(11):667-72.
Liver resection is performed in 15 pigs by means of low divergent Nd YAG laser, the hepatic pedicle being clamped and not. Clamping does not modify the efficiency of laser hemostasis during resection but increases the thickness of the ischemic layer underlying the cut liver edge. The coagulation necrosis and the edematous layer are more thickened. Migration of inflammatory cells and young fibrosis present at day 3 are gaining ground until day 15. During the same period, biliary neoductules and nodules of hepatic regeneration appear. Hepatic inflow being conserved, these reactions are delayed and less intensive. The hyperthermia, the inflammatory cellular reaction and the deepness of parenchymal damages induces by pedicle clamping are suitable for antitumoral surgery. Cooling effects of hepatic inflow are better for traumatic surgery.