Micheli-Tzanakou E
J Med Syst. 1984 Dec;8(6):507-19. doi: 10.1007/BF02321769.
An interactive computer-controlled system is described that is used for visual studies including Visual Evoked Potentials in humans and animals and Visual Receptive Field recordings in animals. Visual stimuli are generated by a display system and the brain activity is monitored by microelectrodes (for animal recordings) and scalp electrodes (for human recordings). The signals are amplified, digitized, and stored. The software uses a response feedback algorithm for mapping the receptive fields. Initially random patterns are presented on a TV monitor and the neural response is recorded. Depending on the response to the pattern and the light distribution in it, the algorithm calculates a new pattern, always trying to maximize the response. As the process goes on, the stimuli patterns become near optimal and thus the receptive field of the neuron is mapped automatically, as a result that for many years has been formed by trial and error. The same system is used for analysis of the recorded results and recordings of the Visual Evoked Potentials in animals and humans. For the human evoked potentials different patterns are generated on the display monitor with a variety of choices, ranging from the simplest (checkerboard and gratings) to the most complicated ones (faces and scenes).
本文描述了一种交互式计算机控制系统，该系统用于视觉研究，包括人类和动物的视觉诱发电位以及动物的视觉感受野记录。视觉刺激由显示系统产生，大脑活动通过微电极（用于动物记录）和头皮电极（用于人类记录）进行监测。信号被放大、数字化并存储。该软件使用响应反馈算法来绘制感受野。最初，随机图案呈现在电视监视器上，并记录神经反应。根据对图案的反应及其光分布，算法计算出新的图案，始终试图使反应最大化。随着过程的进行，刺激图案变得接近最优，从而自动绘制出神经元的感受野，这是一个多年来通过反复试验形成的结果。同一系统用于分析记录结果以及动物和人类视觉诱发电位的记录。对于人类诱发电位，在显示监视器上生成不同的图案，有多种选择，从最简单的（棋盘格和光栅）到最复杂的（面部和场景）。
