The development of a unified physico-chemical research line for studying the relationship between the resorption rates and the physico-chemical properties of drugs.

The developed physico-chemical panel system was tested by partly similar, partly different structures. The system seems to be useful with a high operating efficiency for the calculation and prediction of the absorption rates at different structures. One of the used physico-chemical molecular and system parameters seems to be particularly useful for characterisation of drug absorption. The authors propose the using of dipole moments for prediction of drug absorption, because this physico-chemical constant is calculable on the basis of chemical structures of drugs without measurements, and it characterizes the absorption rates with the largest probability from obtained physico-chemical constants in this panel system. The authors hope that this method will help in decreasing the costs and increasing the efficiency of drug-design.