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[多发性硬化症病因发病机制的流行病学研究]

[Epidemiologic study on the etiopathogenesis of multiple sclerosis].

作者信息

Körting H J, Hindersin P, Küstner R, Müller A, Sachs H

出版信息

Psychiatr Neurol Med Psychol (Leipz). 1984 Dec;36(12):696-701.

PMID:6528002
Abstract

A computer-aided evaluation of those affected with multiple sclerosis (n = 90) with regard to the actually discussed hypothesis on the aetiology of this disease results in 10 significant signs. These signs in their majority support the combined hypothesis of a disturbed regulation of infection and immunity. Frequently, as early as in childhood and youth the upper airways are affected, and this is coupled with a severe course of the disease. The incidence also shows familially and territorially frequent occurrences.

摘要

对90名多发性硬化症患者进行计算机辅助评估,以探讨关于该疾病病因的实际讨论假设,结果发现了10个显著体征。这些体征大多支持感染与免疫调节紊乱的联合假设。通常,早在儿童期和青年期,上呼吸道就会受到影响,且这与疾病的严重病程相关。发病率在家族和地域上也呈现出高发态势。

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