Lubbers W J, Losekoot G, Lam J, Naeff M S
Tijdschr Kindergeneeskd. 1984 Dec;52(6):222-7.
In a cooperative, retrospective, study 120 children are reviewed with preexcitation pattern. 80 patients had tachycardias; 54 children were under 1 year, 49 under 3 months of age at their first attack. In 50% the preexcitation pattern disappeared in the first year of life, allthough intermittent preexcitation could be seen in some patients. In 12 patients a circusmovement tachycardia was proved on the surface ecg; in the group of 63 children with a tachycardia of unknown origin probably more may be caused by this mechanism. A beneficial effect of digoxin in childhood is noticed, with good response in 45 cases. A possible explanation for the difference in effect of digoxin during childhood and in adolescence is discussed.
在一项合作性回顾性研究中，对120例有预激综合征模式的儿童进行了评估。80例患者有心动过速；54例儿童年龄在1岁以下，49例在首次发作时年龄在3个月以下。50%的患者预激综合征模式在出生后第一年内消失，不过在一些患者中可观察到间歇性预激。12例患者体表心电图证实有折返性心动过速；在63例病因不明的心动过速儿童组中，可能有更多是由这种机制引起的。观察到地高辛在儿童期有有益作用，45例反应良好。讨论了地高辛在儿童期和青春期作用差异的可能解释。
