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[麻疹病毒L-16疫苗株及其莫斯科-5克隆株理化特性的比较特征]

[Comparative characteristics of the physicochemical properties of the vaccinal strain of measles virus L-16 and its Moscow-5 clone].

作者信息

Andzhaparidze O G, Koptiaeva I B, Bogomolova N N, Boriskin Iu S, Gordienko N M

出版信息

Vopr Virusol. 1984 Nov-Dec;29(6):691-4.

PMID:6528575
Abstract

Certain physical and chemical properties of the measles virus vaccine strain L-16 and its clonal variant M-5 proposed as a duplicate of the vaccine strain were studied. The buoyant density of both viruses in sucrose was 1.18-1.19 g/cm3. Virions were found to contain 6 structural proteins. Electron microscopic examinations revealed no differences in the morphology of virions of the vaccine L-16 strain and M-5 clone.

摘要

对麻疹病毒疫苗株L-16及其被提议作为疫苗株复制品的克隆变体M-5的某些物理和化学特性进行了研究。两种病毒在蔗糖中的浮力密度均为1.18 - 1.19 g/cm³。发现病毒粒子含有6种结构蛋白。电子显微镜检查显示,疫苗L-16株和M-5克隆的病毒粒子形态没有差异。

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