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[成人巨结肠。关于76例病例]

[Megacolon in adults. Apropos of 76 cases].

作者信息

Parc R, Berrod J L, Tussiot J, Loygue J

出版信息

Ann Gastroenterol Hepatol (Paris). 1984 May-Jun;20(3):133-41.

PMID:6529170
Abstract

27 patients with Hirschsprung's disease and 49 patients with idiopathic megacolon were followed for a period ranging between 6 months and 15 years. The diagnosis is essentially based on the barium enema and functional ano-rectal investigations. Duhamel's operation was performed in 26 patients with Hirschsprung's disease and in 34 patients with idiopathic megacolon. There was no mortality, but 10 cases of pelvic suppuration required colostomy, 9 of which were temporary. 8 cases of anastomotic stenosis developed as a late complication, but they were easily dilated by a simple surgical procedure. One patient developed sexual dysfunction (retrograde ejaculation). A good result was obtained in all patients with Hirschsprung's disease, except for one case of adynamic colon. Two patients with idiopathic megacolon were lost to follow-up. All but two of the remaining patients obtained a good or excellent result. Other operations were performed for idiopathic megacolon: 6 sphincterotomies, with 3 successes and 3 failures; 15 sigmoidectomies, including 3 with sub-peritoneal anastomosis (State's operation). There were 5 good results, 6 mediocre results and 4 failures which subsequently required a Duhamel's operation. Other techniques were performed more rarely: Swenson's operation with a short-term technical failure, 3 side-to-side ileo-sigmoid anastomoses with 3 failures which required a sub-total colectomy with ileo-sigmoid anastomosis. The longterm result was mediocre. The trans-rectal, colo-anal descent of the colon therefore appears to be the treatment of choice in megacolon in adults of whatever cause.

摘要

对27例先天性巨结肠患者和49例特发性巨结肠患者进行了为期6个月至15年的随访。诊断主要基于钡灌肠和功能性肛门直肠检查。26例先天性巨结肠患者和34例特发性巨结肠患者接受了杜哈梅尔手术。无死亡病例,但有10例盆腔化脓需要行结肠造口术,其中9例为暂时性造口。8例吻合口狭窄作为晚期并发症出现,但通过简单的外科手术很容易扩张。1例患者出现性功能障碍(逆行射精)。除1例结肠动力缺乏外,所有先天性巨结肠患者均取得了良好的效果。2例特发性巨结肠患者失访。其余患者中除2例以外,均取得了良好或极佳的效果。针对特发性巨结肠还实施了其他手术:6例括约肌切开术,3例成功,3例失败;15例乙状结肠切除术,其中3例采用腹膜下吻合术(斯泰特手术)。有5例效果良好,6例效果一般,4例失败,失败病例随后需要行杜哈梅尔手术。其他技术实施较少:斯文森手术出现短期技术失败,3例侧侧回肠乙状结肠吻合术均失败,需要行回肠乙状结肠吻合术的次全结肠切除术。长期效果一般。因此,无论病因如何,经直肠结肠肛管下移术似乎是成人巨结肠的首选治疗方法。

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1
[Megacolon in adults. Apropos of 76 cases].[成人巨结肠。关于76例病例]
Ann Gastroenterol Hepatol (Paris). 1984 May-Jun;20(3):133-41.
2
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Total colonic manometry as a guide for surgical management of functional colonic obstruction: Preliminary results.全结肠测压作为功能性结肠梗阻手术治疗的指导:初步结果
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Eur J Pediatr Surg. 1995 Apr;5(2):110-2. doi: 10.1055/s-2008-1066180.
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Chir Pediatr. 1981;22(4):267-71.
7
[Choice of the treatment method in Hirschsprung's disease in adults].[成人先天性巨结肠症治疗方法的选择]
Vestn Khir Im I I Grek. 1980 Apr;124(4):28-32.
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Clinical features' diagnostics and treatment of Hirschsprung's disease in adults.成人先天性巨结肠病的临床特征、诊断及治疗。
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Disparities in the gut metabolome of post-operative Hirschsprung's disease patients.术后先天性巨结肠病患者肠道代谢组的差异。
Sci Rep. 2021 Aug 9;11(1):16167. doi: 10.1038/s41598-021-95589-0.
2
The developmental etiology and pathogenesis of Hirschsprung disease.先天性巨结肠病的发育病因和发病机制。
Transl Res. 2013 Jul;162(1):1-15. doi: 10.1016/j.trsl.2013.03.001. Epub 2013 Mar 22.
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Systematic review of surgical options for idiopathic megarectum and megacolon.特发性巨直肠和巨结肠手术选择的系统评价
Ann Surg. 2005 Apr;241(4):562-74. doi: 10.1097/01.sla.0000157140.69695.d3.
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Hirschsprung disease, associated syndromes, and genetics: a review.先天性巨结肠症、相关综合征与遗传学:综述
J Med Genet. 2001 Nov;38(11):729-39. doi: 10.1136/jmg.38.11.729.
5
Colectomy for idiopathic megarectum and megacolon.特发性巨直肠和巨结肠的结肠切除术。
Gut. 1991 Dec;32(12):1538-40. doi: 10.1136/gut.32.12.1538.
6
Surgery for idiopathic megarectum and megacolon.
Int J Colorectal Dis. 1991 Aug;6(3):171-4. doi: 10.1007/BF00341241.
7
Idiopathic megarectum treated by Duhamel's operation.
J R Soc Med. 1992 Jun;85(6):358-9.
8
Results of stoma formation for idiopathic megarectum and megacolon.
Int J Colorectal Dis. 1992 Jun;7(2):82-4. doi: 10.1007/BF00341291.