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原发性高血压患者红细胞内钾离子流入情况

Potassium influx into erythrocytes in essential hypertension.

作者信息

Bin Talib H K, Chipperfield A R, Semple P F

出版信息

J Hypertens. 1984 Aug;2(4):405-9.

PMID:6530548
Abstract

Sodium plus potassium (Na+K) cotransport in erythrocytes of patients with essential hypertension has mainly been studied elsewhere by measuring net outward frusemide-sensitive Na and K movements. We compared K influx (tracer 86 Rubidium) in control subjects and hypertensives who had never previously been treated for hypertension. The cotransport K influx rates in controls and hypertensives were 0.44 +/- 0.02 (mumol/ml cells/h; mean +/- s.e.; n = 20) and 0.67 +/- 0.06 (mumol/ml cells/h; mean +/- s.e.; n = 23) respectively. The active influxes were 1.03 +/- 0.03 and 2.06 +/- 0.13 (mumol/ml cells/h; mean +/- s.e.) respectively. The variance of both parameters was significantly greater in the hypertensive group but, taking this into account, the differences were significant (P less than 0.01).

摘要

原发性高血压患者红细胞中的钠钾协同转运主要是在其他地方通过测量速尿敏感的钠和钾净外向运动来研究的。我们比较了对照组和从未接受过高血压治疗的高血压患者的钾流入量(示踪剂86铷)。对照组和高血压患者的协同转运钾流入率分别为0.44±0.02(μmol/ml细胞/小时;平均值±标准误;n = 20)和0.67±0.06(μmol/ml细胞/小时;平均值±标准误;n = 23)。主动流入量分别为1.03±0.03和2.06±0.13(μmol/ml细胞/小时;平均值±标准误)。高血压组这两个参数的方差显著更大,但考虑到这一点,差异仍然显著(P小于0.01)。

相似文献

1
Potassium influx into erythrocytes in essential hypertension.原发性高血压患者红细胞内钾离子流入情况
J Hypertens. 1984 Aug;2(4):405-9.
2
Outward Na+-K+-Cl- cotransport function in erythrocytes from essential hypertensives.原发性高血压患者红细胞外向钠-钾-氯协同转运功能
J Hum Hypertens. 1989 Feb;3(1):1-8.
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The regulation of Na-K cotransport system and essential hypertension.钠钾协同转运系统与原发性高血压的调控
Klin Wochenschr. 1985;63 Suppl 3:52-4.
4
Altered erythrocyte cation transport related to hypertension or oral contraception.
Klin Wochenschr. 1985;63 Suppl 3:42-4.
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Comparison of outward and inward Na+/K+ cotransport-mediated fluxes in erythrocytes of essential hypertensive patients. Preliminary results.原发性高血压患者红细胞中外向和内向钠钾协同转运介导的通量比较。初步结果。
Clin Exp Hypertens (1978). 1981;3(4):809-14. doi: 10.3109/10641968109033704.
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[Potassium ion transport in the erythrocytes of the frog Rana ridibunda].[泽蛙红细胞中的钾离子转运]
Zh Evol Biokhim Fiziol. 1995 Mar-Apr;31(2):161-9.
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Erythrocytic sodium ion transport systems in primary and secondary hypertension of the rat.
Kidney Int Suppl. 1982 May;11:S69-75.
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Low sodium cotransport in red cells with physiological internal sodium concentration in essential hypertension.原发性高血压患者红细胞中钠浓度正常时的低钠协同转运
Hypertension. 1984 Nov-Dec;6(6 Pt 1):826-31. doi: 10.1161/01.hyp.6.6.826.
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[Cation flux in erythrocytes of patients with essential hypertension].
Klin Wochenschr. 1983 May 16;61(10):517-21. doi: 10.1007/BF01488719.
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Radioactive 86rubidium influx into red blood cells in essential hypertension in relation to the plasma renin activity.放射性86铷流入原发性高血压患者红细胞的情况与血浆肾素活性的关系
Horm Metab Res. 1984 Jan;16(1):41-5. doi: 10.1055/s-2007-1014689.

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