Bin Talib H K, Chipperfield A R, Semple P F
J Hypertens. 1984 Aug;2(4):405-9.
Sodium plus potassium (Na+K) cotransport in erythrocytes of patients with essential hypertension has mainly been studied elsewhere by measuring net outward frusemide-sensitive Na and K movements. We compared K influx (tracer 86 Rubidium) in control subjects and hypertensives who had never previously been treated for hypertension. The cotransport K influx rates in controls and hypertensives were 0.44 +/- 0.02 (mumol/ml cells/h; mean +/- s.e.; n = 20) and 0.67 +/- 0.06 (mumol/ml cells/h; mean +/- s.e.; n = 23) respectively. The active influxes were 1.03 +/- 0.03 and 2.06 +/- 0.13 (mumol/ml cells/h; mean +/- s.e.) respectively. The variance of both parameters was significantly greater in the hypertensive group but, taking this into account, the differences were significant (P less than 0.01).
原发性高血压患者红细胞中的钠钾协同转运主要是在其他地方通过测量速尿敏感的钠和钾净外向运动来研究的。我们比较了对照组和从未接受过高血压治疗的高血压患者的钾流入量(示踪剂86铷)。对照组和高血压患者的协同转运钾流入率分别为0.44±0.02(μmol/ml细胞/小时;平均值±标准误;n = 20)和0.67±0.06(μmol/ml细胞/小时;平均值±标准误;n = 23)。主动流入量分别为1.03±0.03和2.06±0.13(μmol/ml细胞/小时;平均值±标准误)。高血压组这两个参数的方差显著更大,但考虑到这一点,差异仍然显著(P小于0.01)。