Suduca P, Cuer J C, Suduca J M, Rumeau J L
Ann Gastroenterol Hepatol (Paris). 1984 Dec;20(6):339-45.
The inverted polypoid hamartoma of the rectum (IPHR) is characterized by polypoid masses composed of ectopic glands of Lieberkühn invaginated within the mucosal muscle to form a conglomeration in the submucosa, hence the term "inverted polyp". It produces an unremarkable rectal syndrome, more suggestive, when abundant glairy exudate is observed, in young subjects. It causes a unique sessile polypoid lesion, occasionally multilobular or a stenotic, approximately circular, ring. Diagnosis is made using deep surgical biopsies. Two theories, dysgenetic or acquired, attempt to explain the pathogenesis of this lesion. The predominant acquired theory includes IPHR in the "solitary rectal ulcer" syndrome which is related to the traumatism of rectal prolapse. Transanal ablation is the predominant treatment.
直肠内翻性息肉样错构瘤（IPHR）的特征是息肉样肿物，由内陷至黏膜肌层内的Lieberkühn异位腺组成，在黏膜下层形成团块，因此有“内翻性息肉”这一术语。它引起的直肠综合征不明显，在年轻患者中，当观察到大量黏液性渗出物时更具提示性。它导致一种独特的无蒂息肉样病变，偶尔为多叶状或狭窄的、近似圆形的环状病变。诊断需采用深部手术活检。有两种理论，即发育异常理论或后天获得理论，试图解释该病变的发病机制。主要的后天获得理论将IPHR归入“孤立性直肠溃疡”综合征，该综合征与直肠脱垂的创伤有关。经肛门切除术是主要的治疗方法。
