Machino M, Morioka H, Tachibana M, Tsuruoka T, Mizukoshi O
Arch Histol Jpn. 1984 Nov;47(5):549-51. doi: 10.1679/aohc.47.549.
Using a protein A-gold immunohistochemical technique, the lysozyme rich core and the lysozyme free peripheral rim were differentiated in the secretory granule of the serous cell in the human nasal mucosa, under the electronmicroscope. The shperical lysozyme rich core, which had been excreted into the gland lumen, was also wrapped with the peripheral rim. This finding suggests that the peripheral rim defends the integrity of the core and inhibits the release of lysozyme from the core.
利用蛋白A-金免疫组织化学技术，在电子显微镜下对人鼻黏膜浆液性腺细胞分泌颗粒中富含溶菌酶的核心部分和不含溶菌酶的外周边缘部分进行了区分。已分泌到腺腔内的球形富含溶菌酶的核心部分也被外周边缘所包裹。这一发现表明外周边缘保护核心部分的完整性，并抑制溶菌酶从核心部分释放。
