Holbach K H, Wappenschmidt J, Sanchez F
Rontgenblatter. 1978 May;31(5):276-81.
An extra-intracranial anastomosis operation was carried out in 60 stroke patients in order to bypass the occlusion or severe stenosis in the internal carotid or middle cerebral artery. Postoperative angiographical follow-up studies showed a well functioning extra-intracranial bypass in more than 90 % of the patients. In many cases repeat angiography done weeks or months following surgery revealed an enlargement of the caliber of the extracranial artery used for constructing the bypass and also of the cerebral arteries that were irrigated by the bypass. Furthermore we noted that the new collateral channel was able to fill a steadely increasing part of the cerebral circulation and that it was also found to irrigate territories of the brain that were previously well perfused by leptomeningeal anastomosis or retrograd flow through the ophthalmic artery etc. resulting in a reversal of the direction of blood flow in these collaterals. The neurological follow-up examinations revealed that the increase in cerebral blood supply following the extra-intracranial anastomosis operation resulted in a considerable improvement of the post-stroke neurological deficits.
对60例中风患者进行了颅内外吻合手术，以绕过颈内动脉或大脑中动脉的闭塞或严重狭窄。术后血管造影随访研究显示，超过90%的患者颅内外搭桥功能良好。在许多情况下，术后数周或数月进行的重复血管造影显示，用于构建搭桥的颅外动脉以及由搭桥供血的脑动脉管径增大。此外，我们注意到新的侧支通道能够填充越来越多的脑循环部分，并且还发现它能够灌注以前通过软脑膜吻合或通过眼动脉逆行血流等充分灌注的脑区，导致这些侧支中血流方向逆转。神经学随访检查显示，颅内外吻合手术后脑供血增加导致中风后神经功能缺损有相当大的改善。
