人胎盘组织中催产素样物质的免疫组织化学研究

Immunohistochemical study on oxytocin-like substance in the human placenta.

作者信息

Nakazawa K, Makino T, Iizuka R, Kohsaka S, Tsukada Y

出版信息

Endocrinol Jpn. 1984 Dec;31(6):763-8. doi: 10.1507/endocrj1954.31.763.

DOI:10.1507/endocrj1954.31.763

Abstract

Our previous studies have demonstrated that a large quantity of oxytocin (OT)-like substance exists in human placental tissue. In the present study, the localization of the OT-like substance in the human placenta was investigated by the PAP (peroxidase and antiperoxidase complex) immunohistochemical method. The results demonstrated that the site of syncytiotrophoblast was positively stained by specific antiserum to OT, whereas the tissue was not significantly stained by normal rabbit serum (NRS). These results suggest that the OT-like substance might be localized in syncytiotrophoblast of the placental tissue.

摘要

我们之前的研究表明，人胎盘组织中存在大量催产素（OT）样物质。在本研究中，采用PAP（过氧化物酶和抗过氧化物酶复合物）免疫组织化学方法研究了OT样物质在人胎盘中的定位。结果表明，用OT特异性抗血清对合体滋养层细胞进行染色呈阳性，而用正常兔血清（NRS）染色时组织无明显染色。这些结果提示，OT样物质可能定位于胎盘组织的合体滋养层细胞中。