[The failures of D penicillamine].

On the basis or a study of 50 cases of rheumatoid polyarthritis treated with D penicillamine comments are made on the failure of this form of treatment by comparison of the apparent and real efficacy. Taking account of withdrawals the percentage of true success is no more than a quarter of the patients treated with D penicillamine. Failure are due to overall inefficacy, dropouts from treatment and intolerance. The practical data on the indications and contra-indications of treatment, its conduct and supervision are defined.