在常氧条件下对门腔静脉吻合术（PCA）大鼠静息骨骼肌局部氧分压的测量。

Measurements of local PO2 in the resting skeletal muscles of rats with portocaval anastomosis (PCA) under normoxic conditions.

作者信息

Heinrich R, Grauer W, Schomerus H, Günderoth M, Hoeper J, Kessler M

出版信息

Adv Exp Med Biol. 1984;180:623-8. doi: 10.1007/978-1-4684-4895-5_60.

Abstract

Direct measurements of local oxygen pressure by means of platinum multiwire electrode were performed in rats to investigate the effect of an end-to-side portocaval shunt procedure on muscle tissue oxygenation. Compared with intact rats and/or sham operated animals, rats with portocaval anastomosis showed a significant increase of muscle tissue oxygenation with nearly bellshaped pO2 histograms. This considerable increase in tissue oxygenation might appear to be due to the well known PCA induced hyperdynamic cardiovascular state.

摘要

通过铂多丝电极对大鼠进行局部氧压的直接测量，以研究端侧门腔分流术对肌肉组织氧合的影响。与完整大鼠和/或假手术动物相比，门腔吻合术大鼠的肌肉组织氧合显著增加，pO2直方图接近钟形。组织氧合的这种显著增加似乎可能是由于众所周知的门静脉分流术诱导的高动力心血管状态。