Bertrand J C, Guilbert F, Vaillant J M, Szpirglas H, Chomette G, Auriol M, Mercier C
Ann Otolaryngol Chir Cervicofac. 1984;101(8):607-13.
Prognosis in 11 cases of hemangiopericytoma of the orofacial region (9 buccal and 2 parotid tumors) was, as with these lesions in other zones, an uncertain entity: 4 local recurrences within 8 months to 7 years; one fatal outcome after 3 years from pulmonary micrometastases. Histologic classification of these tumors into 3 cytologic groups of increasing malignancy (I to III) is a function of the number of their cytologic anomalies. They are also divided according to their overall morphology into poorly differentiated, differentiated and sclerous types. Positive correlations between structure and cytologic criteria of malignancy and structure and clinical course have been demonstrated. Ultrastructural examination in 2 cases showed polymorphic endothelial, fibroblastic and smooth muscle cells in contact with adult tumoral pericytes. This suggests the origin of the tumor from young cells of multiple potency rather than from adult pericytes.
11例口面部血管外皮细胞瘤（9例颊部肿瘤和2例腮腺肿瘤）的预后，与其他部位的这些病变一样，并不确定：8个月至7年内有4例局部复发；3年后因肺微转移导致1例死亡。根据这些肿瘤的细胞异常数量，将其组织学分为3个恶性程度递增的细胞组（I至III）。它们还根据整体形态分为低分化型、分化型和硬化型。已证实恶性肿瘤的结构与细胞学标准之间以及结构与临床病程之间存在正相关。2例的超微结构检查显示多形性内皮细胞、成纤维细胞和平滑肌细胞与成年肿瘤性周细胞接触。这表明肿瘤起源于多能的年轻细胞而非成年周细胞。
