Wallace D M, Smith J H, Billington S, Smith M R, Stemplewski H E, Tipton P W
Br J Urol. 1984 Dec;56(6):658-62. doi: 10.1111/j.1464-410x.1984.tb06140.x.
An experimental study was performed to assess the possible tumour-promoting action of urothelial trauma caused by repeated intravesical diathermy, catheterisation, and the instillation of water, glycine and saline in the rat bladder which had previously been exposed to an initiating dose of the carcinogen N-methyl-N-nitrosourea. An increase in tumours and inflammatory changes was observed, especially in the group treated with water, and the significance of the findings is discussed.
进行了一项实验研究，以评估在先前已接受致癌剂N-甲基-N-亚硝基脲起始剂量处理的大鼠膀胱中，反复进行膀胱内热疗、插管以及灌注水、甘氨酸和生理盐水所引起的尿路上皮创伤可能具有的促肿瘤作用。观察到肿瘤和炎症变化有所增加，尤其是在接受水灌注的组中，并对这些发现的意义进行了讨论。
