Buchanan N
S Afr Med J. 1978 Jan 21;53(3):103-5.
The value of serum drug assays in clinical practice is assessed, and it is concluded that, except in neonates, elderly persons or patients with hepatic and renal dysfunction, such assays are of little clinical value. However, research projects to obtain clinically applicable pharmacokinetic data are of great value. Routine clinical drug assays should be discouraged on clinical, practical and economic grounds.
评估了血清药物分析在临床实践中的价值,得出的结论是,除了新生儿、老年人或肝肾功能不全的患者外,此类分析几乎没有临床价值。然而,获取临床适用药代动力学数据的研究项目具有很大价值。基于临床、实际和经济原因,应不鼓励进行常规临床药物分析。