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心血管疾病患者静脉注射镁后钾离子的细胞内外转移

Intra-/extracellular shifts of potassium after the administration of Mg in patients with cardiovascular diseases.

作者信息

Dyckner T, Wester P O

出版信息

Magnesium. 1984;3(4-6):339-45.

PMID:6536841
Abstract

Body potassium status is often dosed on serum potassium determinations. However, this parameter is not an adequate guide to the body potassium status, unless several factors are taken into consideration, e.g. acid-base balance and serum creatinine level. Muscle magnesium content is another factor, probably operative through its activation of Na-K-ATPase, which produces the energy necessary for the active transport of potassium into the cell. Magnesium has a membrane-stabilizing effect as well, diminishing the outward movement of potassium from the cell. In case of magnesium deficiency, potassium cannot be transported into the cell in sufficient amounts and the result is an imbalance between the intra- and the extracellular potassium concentration, which in turn may lead to cardiac dysrhythmias.

摘要

身体钾状态通常通过血清钾测定来衡量。然而,除非考虑几个因素,如酸碱平衡和血清肌酐水平,否则该参数并不能充分反映身体的钾状态。肌肉镁含量是另一个因素,可能通过激活钠钾ATP酶起作用,该酶产生钾主动转运进入细胞所需的能量。镁还具有膜稳定作用,减少钾从细胞向外移动。在镁缺乏的情况下,钾无法充分转运到细胞内,结果是细胞内和细胞外钾浓度失衡,进而可能导致心律失常。

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Intra-/extracellular shifts of potassium after the administration of Mg in patients with cardiovascular diseases.心血管疾病患者静脉注射镁后钾离子的细胞内外转移
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Interactions of magnesium and potassium in the pathogenesis of cardiovascular disease.镁与钾在心血管疾病发病机制中的相互作用。
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Refractory potassium repletion. A consequence of magnesium deficiency.难治性补钾。镁缺乏的一个后果。
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