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一项关于猴子新皮质嗅觉区域神经通路的辣根过氧化物酶研究。

An HRP study of neural pathways to neocortical olfactory areas in monkeys.

作者信息

Naito J, Kawamura K, Takagi S F

出版信息

Neurosci Res. 1984 Feb;1(1):19-33. doi: 10.1016/0168-0102(84)90027-0.

DOI:10.1016/0168-0102(84)90027-0
PMID:6536884
Abstract

Afferent fiber projections to the two orbitofrontal olfactory areas of monkeys were studied using the horseradish peroxidase (HRP) technique. After injections of HRP into the lateroposterior (LPOF) or centroposterior (CPOF) area of the orbitofrontal cortex, some differences were found in the distribution of labeled cells between the projections to the LPOF and CPOF. These results, along with those of previous electrophysiological investigations, suggest the following conclusions: (1) the extrathalamic olfactory pathway to the LPOF identified by Tanabe et al. has relay neurons primarily in the substantia innominata and the amygdala and, secondarily, in the prorhinal cortex and the hypothalamus; (2) direct fibers to the LPOF from the amygdala and the prorhinal cortex pass through the areas ventral to the thalamus; (3) the transthalamic olfactory pathway to the CPOF identified by Yarita et al. has relay neurons concentrated primarily in the magnocellular portion of the mediodorsal nucleus of the thalamus.

摘要

采用辣根过氧化物酶(HRP)技术研究了传入纤维向猴的两个眶额嗅觉区的投射。将HRP注入眶额皮质的后外侧(LPOF)或中央后(CPOF)区后,发现投射到LPOF和CPOF的标记细胞分布存在一些差异。这些结果与先前的电生理研究结果一起,得出以下结论:(1)田边等人确定的通向LPOF的丘脑外嗅觉通路主要在无名质和杏仁核中有中继神经元,其次在嗅前皮质和下丘脑;(2)来自杏仁核和嗅前皮质的直接纤维通向LPOF时穿过丘脑腹侧区域;(3)矢田等人确定的通向CPOF的丘脑嗅觉通路的中继神经元主要集中在丘脑背内侧核的大细胞部分。

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