Hirai N, Uchino Y
Neurosci Res. 1984 Oct;1(5):327-40. doi: 10.1016/0168-0102(84)90037-3.
Floccular influence on excitatory vestibular reflex arcs of anterior semicircular canal origin was examined in the anaesthetized cat. Stimulation of the anterior semicircular canal nerve (ACN) evoked disynaptic excitatory postsynaptic potentials (EPSPs) in all sampled inferior oblique (IO), superior rectus (SR), and biventor cervicis (BIV) muscle motoneurones of the contralateral side. Conditioning stimulus to the flocculus depressed the amplitude of the EPSPs in both IO and SR motoneurones by 50% on the average but not in any BIV motoneurones. The excitatory vestibulo-ocular neurones identified by orthodromic and antidromic responses to stimulation of the ACN and the contralateral IO motoneurone pool, respectively, were classified as VOC (vestibulo-ocular neurones with axons descending to the cervical segment) or VO (vestibulo-ocular proper) neurones on the basis of whether or not they responded antidromically to stimulation of the spinal cord in the C1 segment. All of the VO neurones in the superior vestibular nucleus (n = 19) were inhibited from the flocculus while the activities of three-fourths of the VO neurones (36/48) in the other vestibular nuclei were not suppressed by floccular stimulation. In contrast, none of VOC neurones (n = 49) received floccular inhibition. Besides inhibition, floccular stimulation induced the antidromic or orthodromic responses in some VO and VOC neurones.
在麻醉猫中研究了绒球对起源于前半规管的兴奋性前庭反射弧的影响。刺激前半规管神经（ACN）可在对侧所有采样的下斜肌（IO）、上直肌（SR）和颈二腹肌（BIV）运动神经元中诱发双突触兴奋性突触后电位（EPSP）。对绒球的条件刺激使IO和SR运动神经元中EPSP的幅度平均降低50%，但对任何BIV运动神经元均无影响。分别通过对ACN刺激的顺行和逆行反应以及对侧IO运动神经元池鉴定出的兴奋性前庭眼神经元，根据它们是否对C1节段脊髓刺激产生逆行反应，被分类为VOC（轴突下行至颈段的前庭眼神经元）或VO（真性前庭眼）神经元。前庭上核中的所有VO神经元（n = 19）均受到绒球的抑制，而其他前庭核中四分之三的VO神经元（36/48）的活动未被绒球刺激所抑制。相比之下，VOC神经元（n = 49）均未受到绒球的抑制。除了抑制作用外，绒球刺激还在一些VO和VOC神经元中诱发了逆行或顺行反应。
