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47,XXY克氏综合征男孩的半球侧化

Hemispheric lateralization in 47,XXY Klinefelter's syndrome boys.

作者信息

Netley C, Rovet J

出版信息

Brain Cogn. 1984 Jan;3(1):10-8. doi: 10.1016/0278-2626(84)90002-2.

DOI:10.1016/0278-2626(84)90002-2
PMID:6537238
Abstract

Thirty-two boys with a 47,XXY karyotype were compared with chromosomally normal male controls in their performance on six tasks of hemispheric specialization. The results revealed that the 47,XXY subjects had smaller asymmetries on left hemisphere tasks and larger asymmetries on right hemisphere tasks than controls. Analyses of individual right and left side scores revealed that the atypical lateral asymmetries of the 47,XXYs were due to a shift toward greater right hemisphere involvement on four of the six measures. It was postulated that the slower fetal growth rates of the extra X chromosome group might contribute to their atypical hemispheric specialization and the failure of their left hemisphere to gain dominance over their right in language processing.

摘要

对32名核型为47,XXY的男孩与染色体正常的男性对照组进行了六项半球特化任务表现的比较。结果显示,与对照组相比,47,XXY受试者在左半球任务上的不对称性较小,而在右半球任务上的不对称性较大。对个体左右侧分数的分析表明,47,XXY个体的非典型侧向不对称是由于在六项测量中的四项上向更大程度的右半球参与转变所致。据推测,额外X染色体组胎儿生长速度较慢可能导致其非典型的半球特化,以及其左半球在语言处理中未能超过右半球占主导地位。

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