Chaikhouni A, Crawford F A, Sade R M, Taylor A B, Riopel D A, Hohn A R
Clin Cardiol. 1984 May;7(5):289-93. doi: 10.1002/clc.4960070507.
From 1971-1981, 18 patients with discrete subaortic stenosis were treated surgically at the Medical University of South Carolina. Echocardiography was diagnostic in 10 of 11 patients in whom it was used. Preoperative cardiac catheterization was performed in all patients. The preoperative left ventricular outflow systolic pressure gradient was 82.0 +/- 27.2 mmHg (mean +/- SD) (range 30-145). In 16 (88.8%) patients excision of the subaortic membrane was complete, and relief of left ventricular outflow obstruction was good. The excision was incomplete in 2 patients; one required reoperation for residual gradient and developed complete heart block, and the other had a residual gradient of 60 mmHg and was in New York Heart Association functional class II when lost to follow-up. These data suggest that complete excision of the discrete subaortic stenosis is important to achieve good relief of left ventricular outflow obstruction.
1971年至1981年期间，南卡罗来纳医科大学对18例孤立性主动脉瓣下狭窄患者进行了手术治疗。11例接受超声心动图检查的患者中有10例通过该检查得以确诊。所有患者均进行了术前心导管检查。术前左心室流出道收缩压梯度为82.0±27.2 mmHg（均值±标准差）（范围30 - 145）。16例（88.8%）患者的主动脉瓣下隔膜切除彻底，左心室流出道梗阻解除效果良好。2例患者的切除不彻底；其中1例因残留梯度需再次手术，并发完全性心脏传导阻滞，另1例残留梯度为60 mmHg，失访时纽约心脏病协会心功能分级为Ⅱ级。这些数据表明，彻底切除孤立性主动脉瓣下狭窄对于有效解除左心室流出道梗阻至关重要。
