Michael P
Dev Biol. 1984 May;103(1):109-16. doi: 10.1016/0012-1606(84)90012-5.
In the present study, when carefully demarcated areas of blastula animal cap were combined with the vegetative yolk mass, PGCs occurred only in those combinations which included the equatorial marginal zone of the animal cap. Furthermore, removal of the vegetative yolk mass as early as stage 6 1/2 did not affect the formation of PGCs. On the basis of these and other observations it is suggested that in urodeles, as in anurans, PGCs may develop from specific cells which nevertheless differentiate into PGCs only when suitable mesodermal elements are formed.
在本研究中，当将囊胚动物帽仔细划分的区域与营养性卵黄块结合时，原始生殖细胞（PGCs）仅出现在那些包含动物帽赤道边缘区的组合中。此外，早在第6.5期去除营养性卵黄块并不影响原始生殖细胞的形成。基于这些及其他观察结果，有人提出，在有尾两栖类中，如同在无尾两栖类中一样，原始生殖细胞可能由特定细胞发育而来，不过这些细胞只有在形成合适的中胚层成分时才会分化为原始生殖细胞。
