Alloussi S, Loew F, Mast G J, Wolf D
Urologe A. 1984 Jan;23(1):39-45.
Hyperreflexive detrusor instability causes severe impairment of the patients private and professional life. Involuntary detrusor contractions lead to incontinence. The results of previous pharmacological and operative therapeutic procedures are unsatisfactory. 22 cases with idiopathic hyperreflexive detrusor instability were cured by selective local anaesthesia of both sacral roots S3. The follow-up period ranges from 4 months to 2 years. In case with neurogenic detrusor instability local anaesthesia of the sacral roots S3 has no permanent effect. But in 4 such cases it was possible to reach continence by permanent interruption of the roots S3 using phenolglycerin injections. Unavoidably this success, which enables social rehabilitation, results in voiding disturbance of the bladder which makes voiding by manual bladder compression or even catheterization necessary.
逼尿肌反射亢进性不稳定会严重损害患者的个人生活和职业生活。逼尿肌不自主收缩会导致尿失禁。以往的药物和手术治疗方法效果均不理想。22例特发性逼尿肌反射亢进性不稳定患者通过选择性骶神经根S3局部麻醉得以治愈。随访期为4个月至2年。对于神经源性逼尿肌不稳定患者，骶神经根S3局部麻醉没有持久效果。但在4例此类患者中，通过注射酚甘油永久性阻断S3神经根，实现了尿失禁控制。不可避免的是，这种能实现社会康复的成功会导致膀胱排尿障碍，使得需要通过手动挤压膀胱甚至导尿来排尿。
