Maruyama Y, Aoki N, Suzuki Y, Sinohara H, Yamamoto T
Acta Endocrinol (Copenh). 1984 Jul;106(3):428-32. doi: 10.1530/acta.0.1060428.
A radioimmunoassay for human sex-steroid-binding plasma protein (SBP) was developed. With this assay, SBP was determined in sera of 138 normal men and 169 non-pregnant women, ranging in age from 11 to 87 years. The results indicate that SBP levels in both sexes increase gradually with age up to mid-eighties, that the average levels in mid-eighties are approximately twice those in early twenties, and that the average levels in women are about twice as high as those in men of corresponding age. These results may also account for the discrepancies in the previous papers regarding the normal blood levels and sexual difference of SBP in adult men and women.
开发了一种用于检测人血浆性类固醇结合蛋白（SBP）的放射免疫分析方法。采用该分析方法，对138名年龄在11至87岁之间的正常男性和169名未怀孕女性的血清进行了SBP检测。结果表明，两性的SBP水平均随年龄增长而逐渐升高，直至八十多岁中期，八十多岁中期的平均水平约为二十出头时的两倍，且女性的平均水平约为同龄男性的两倍。这些结果也可能解释了先前文献中关于成年男性和女性SBP正常血水平及性别差异的差异。
