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多胎妊娠合并不育的系谱

[Pedigree in which multiple pregnancy is combined with sterility].

作者信息

Golubovskiĭ M D

出版信息

Genetika. 1984 Jun;20(6):1052-5.

PMID:6540217
Abstract

A case of simultaneous hereditary transmission of twinning and sterility in a jewish family from Novosibirsk is described. The both characters are transmitted by male and female. It is suggested that twinning and sterility are connected with the action of one dominant mutation with multiple pleiotropic action on propagation system. The action of two alleles in homozygotes is additive. The importance of special search for and study of similar situations for understanding mechanisms of twinning and sterility occurrence in man is discussed.

摘要

本文描述了新西伯利亚一个犹太家庭中同时出现双胞胎遗传和不育遗传的案例。这两种性状均可由男性和女性遗传。研究表明,双胞胎现象和不育与一个对生殖系统具有多效性作用的显性突变有关。纯合子中两个等位基因的作用具有累加性。文中还讨论了专门寻找和研究类似情况对于理解人类双胞胎现象和不育发生机制的重要性。

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