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产后窝仔数对大鼠生长和繁殖的影响。

Postnatal litter size effects on growth and reproduction in rats.

作者信息

Azzam S M, Nielsen M K, Dickerson G E

出版信息

J Anim Sci. 1984 Jun;58(6):1337-42. doi: 10.2527/jas1984.5861337x.

DOI:10.2527/jas1984.5861337x
PMID:6540258
Abstract

The effects of postnatal litter size on pre- and postweaning growth, daughter's litter size and rebreeding performance of the dam were examined in rats that had undergone 14 generations of selection for rate (LG) or efficiency (LE) of postweaning protein gain followed by relaxed selection, and in a randomly selected control line (C). Data came from generations 23 to 24 (standardized litters) and 25 to 26 (unstandardized litters). Generation 25 dams were remated at weaning for two additional parities. Regressions of average pup weight on average postnatal litter size were negative and increased in magnitude from birth to weaning, but decreased with parity number. Average litter size from birth to weaning (3 wk) affected postweaning weights at 5 and 7 wk, but compensatory growth occurred, especially during wk 3 to 5. The effect of dam's litter size (the litter in which the daughter was born) on daughter's weight was still negative and significant at mating and affected litter size of daughters. This negative maternal effect on daughter's litter size was larger when the dam's litter was not standardized. Litter size weaned also affected rebreeding interval of females.

摘要

在经过14代断奶后蛋白质增加速率(LG)或效率(LE)选择然后放松选择的大鼠以及随机选择的对照品系(C)中,研究了产后窝仔数对断奶前后生长、母鼠女儿的窝仔数和再繁殖性能的影响。数据来自第23至24代(标准化窝仔)和第25至26代(非标准化窝仔)。第25代母鼠在断奶时再次交配,进行另外两胎繁殖。平均幼崽体重对平均产后窝仔数的回归呈负相关,且从出生到断奶其幅度增加,但随胎次增加而减小。从出生到断奶(3周)的平均窝仔数影响5周和7周时的断奶后体重,但出现了补偿性生长,尤其是在第3至5周。母鼠窝仔数(女儿出生的窝)对女儿体重的影响在交配时仍为负且显著,并影响女儿的窝仔数。当母鼠的窝不标准化时,这种对女儿窝仔数的负面母体效应更大。断奶时的窝仔数也影响雌性的再繁殖间隔。

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