Udod V M, Trofimenko S P, Shabash E G, Storozhuk V T
Vestn Khir Im I I Grek. 1984 Jun;132(6):48-51.
Experimental injections of a home-made proteolytic enzyme of vegetative origin--papain--in doses 5 to 36 mg/kg have not provoked any toxic effect upon the body and the serous membranes. The clinical use of 0.2-0.5% papain solution for the local treatment of purulent processes has proved its high proteolytic activity and its ability to shorten the first phase of the wound process. The preparation does not cause any local or general complications and can be successfully used in purulent surgery in hospital and in out-patient practice.
实验性注射自制的源自植物的蛋白水解酶——木瓜蛋白酶，剂量为5至36毫克/千克，未对身体和浆膜产生任何毒性作用。0.2 - 0.5%木瓜蛋白酶溶液用于局部治疗化脓性病症的临床应用已证明其具有高蛋白水解活性，以及缩短伤口愈合第一阶段的能力。该制剂不会引起任何局部或全身并发症，可成功用于医院和门诊的化脓性外科手术。
