Drummond P D, Lance J W
Neurology. 1984 Oct;34(10):1292-8. doi: 10.1212/wnl.34.10.1292.
Eleven patients were examined thermographically during spontaneous cluster headaches and 22 during attacks induced by nitroglycerin or alcohol. In cluster headache, heat loss increased from the affected orbital region, and in some patients, this spread above and below the eye, down the nose, and to the affected temple. Inhalation of 100% oxygen reduced or abolished cluster pain in 22 of 25 instances, and asymmetry of heat loss then disappeared. Since the unilateral increase in blood flow usually followed the onset of pain in affected areas, the vascular changes of cluster headache are probably secondary phenomena, initiated by a vasodilator pathway, with the trigeminal nerve as the afferent and the greater superficial petrosal nerve as the efferent limb.
11名患者在丛集性头痛发作期间接受了热成像检查，22名患者在由硝酸甘油或酒精诱发的发作期间接受了检查。在丛集性头痛中，患侧眼眶区域的热量散失增加，在一些患者中，这种现象会扩散到眼睛上方和下方、鼻子以及患侧颞部。25例中有22例吸入100%氧气后丛集性疼痛减轻或消失，随后热量散失的不对称性也消失了。由于患侧区域血流的单侧增加通常在疼痛发作后出现，丛集性头痛的血管变化可能是继发现象，由血管舒张途径引发，三叉神经为传入神经，岩浅大神经为传出神经。
