Schmitz A, Meyer U, Kierfeld G, Küchemann K
Urologe A. 1984 Sep;23(5):278-80.
The exfoliative cytology of the urinary bladder is helpful in the detection of occult bladder carcinoma, which in according to definition is not recognizable without magnification, as well as in the follow-up of treated bladder carcinoma. Within a period of 5 years 23 occult bladder carcinomas were detected by cytological studies alone. The degree of malignancy of the established transitional cell carcinoma varied between G2 and G3. The latent period between the found cytological result and the histological confirmation amounted to 14 months. In our experience the diagnosis of occult bladder carcinoma can be established by exfoliative cytology of the urinary bladder, if invisible parts of tumor with moderate and high degree of malignancy communicate with the mucosa of the bladder. The cytological recognition of malignant cells of urothelium offers valuable support for further therapeutic procedures, if there is no cystoscopic evidence of tumor in the bladder. In addition to clinical diagnosis of bladder cancer exfoliative cytology of the urinary bladder should also be part of the follow-up of treated bladder cancer.
膀胱脱落细胞学检查有助于隐匿性膀胱癌的检测，根据定义，这种癌在未放大的情况下无法识别，同时也有助于已治疗膀胱癌的随访。在5年的时间里，仅通过细胞学研究就检测出了23例隐匿性膀胱癌。确诊的移行细胞癌的恶性程度在G2和G3之间。从发现细胞学结果到组织学确诊的潜伏期为14个月。根据我们的经验，如果恶性程度为中度和高度的肿瘤不可见部分与膀胱黏膜相通，那么隐匿性膀胱癌的诊断可以通过膀胱脱落细胞学检查来确立。如果膀胱镜检查未发现膀胱肿瘤，尿路上皮恶性细胞的细胞学识别可为进一步的治疗程序提供有价值的支持。除了膀胱癌的临床诊断外，膀胱脱落细胞学检查也应作为已治疗膀胱癌随访的一部分。
