Tanoguchi H, Otuska A, Morozumi K, Kobayashi K, Shirobe T, Umezono A, Miyashita J
Gan No Rinsho. 1984 Dec;30(15):1942-6.
A case of gastric cancer which contained a part of choriocarcinoma was reported in this study. The patient was a 64-year-old man, who was operated on with the diagnosis of gastric cancer in the prepyloric region. The postoperative histological examination revealed that typical choriocarcinoma was noted in a part of the adenocarcinoma, which occupied almost the entire portion of the surgical specimen. In addition, the precise localization of human chorionic gonadotropin (hCG) in the portion of choriocarcinoma was proved by the indirect immunoperoxidase stain (PAP method). The patient showed the gynecomastia clinically. The concentration of postoperative serum hCG was elevated and testicular abnormality was not noted clinically.
本研究报告了一例含有部分绒毛膜癌成分的胃癌病例。患者为一名64岁男性,因胃幽门区癌接受手术治疗。术后组织学检查显示,在几乎占据手术标本整个部分的腺癌中,部分区域可见典型的绒毛膜癌。此外,通过间接免疫过氧化物酶染色(PAP法)证实了绒毛膜癌部分人绒毛膜促性腺激素(hCG)的精确定位。患者临床上出现了男性乳房发育。术后血清hCG浓度升高,临床上未发现睾丸异常。