Konstantinov N, Khadzhiolov A
Vet Med Nauki. 1984;21(9):57-67.
Unilateral ovariectomy was carried out of thirty female rats of the Wistar race, aged 45 days. The morphologic changes in the remaining functional ovary were followed up in compliance with the phase of the estrus cycle of the investigated animals. It was established that the greater size of the hyperthrophic ovary was due to the faster growth of follicles as well as to the increased number of corpora aliena and the strongly proliferated interstitium. In metestrus and diestrus there was also a faster process of follicular atresia. During the proestrus-estrus phase these processes involved mainly the preovulatory follicles. The morphologic changes observed in the functioning follicle were primarily due to the releasing factors and the gonadotropic hormones of the hypothalamo-hypophysial system the normal level of which proved high as they acted not on two, but on one gonad.
对30只45日龄的Wistar品系雌性大鼠实施单侧卵巢切除术。根据被研究动物发情周期的阶段，对剩余功能卵巢的形态学变化进行跟踪。结果发现，肥大卵巢体积增大是由于卵泡生长加快、异体黄体数量增加以及间质强烈增殖。在间情期和动情后期，卵泡闭锁过程也更快。在发情前期至发情期，这些过程主要涉及排卵前卵泡。在功能卵泡中观察到的形态学变化主要归因于下丘脑 - 垂体系统的释放因子和促性腺激素，由于这些激素作用于一个而非两个性腺，其正常水平被证明较高。
