Arnold R, McIntosh C, Bothe E, Koop H
Z Gastroenterol. 1978 May;16(5):317-24.
Pancreatic polypeptide (PP) can be reproducible measured in serum and tissue extracts by mean of a standardized radioimmunoassay. Dispite extensive investigations into the biological actions of the polypeptide and a range of radioimmunological measurements in serum and tissue the physiological significance of PP is, at present, unclear. The normal postprandial increase of serum PP levels has been reported to be lacking after vagotomy and reduced in patients with chronic pancreatitis. If these observations can be confirmed then PP measurement may be a clinically usefull criterion as to the effectiveness of vagotomy and as an indicator for chronic pancreatic disease.
通过标准化放射免疫测定法可在血清和组织提取物中重复性地检测胰多肽（PP）。尽管对该多肽的生物学作用进行了广泛研究，并对血清和组织进行了一系列放射免疫测定，但目前PP的生理意义尚不清楚。据报道，迷走神经切断术后血清PP水平餐后正常升高消失，慢性胰腺炎患者血清PP水平降低。如果这些观察结果能够得到证实，那么PP检测可能成为判断迷走神经切断术效果的一项临床有用标准，以及慢性胰腺疾病的一个指标。
