戈谢病中睑裂斑的病理学

The pathology of pingueculae in Gaucher's disease.

作者信息

Chu F C, Rodrigues M M, Cogan D G, Barranger J A

出版信息

Ophthalmic Paediatr Genet. 1984 Apr;4(1):7-11. doi: 10.3109/13816818409009887.

Abstract

Several reports have noted an apparent association between pingueculae and Gaucher's disease and suggested that the yellow coloring of these lesions is attributable to Gaucher cells. The authors biopsied pingueculae from ten patients with this disorder and examined them by serial light microscopy and electron microscopy. They failed to find Gaucher cells in any specimen, but, as typical for pingueculae, the elastosis observed histologically could account for their yellow hue.

摘要

几份报告指出睑裂斑与戈谢病之间存在明显关联，并认为这些病变的黄色素沉着可归因于戈谢细胞。作者对10例患有该疾病患者的睑裂斑进行活检，并通过连续光学显微镜和电子显微镜进行检查。他们在任何标本中均未发现戈谢细胞，但从组织学上观察到的弹性组织变性，作为睑裂斑的典型特征，可以解释其黄色色调。