Waxman M B, Wald R W, Cameron D
Cardiol Clin. 1983 May;1(2):143-85.
We have endeavoured to present an integrated and dynamic overview of the interaction between the autonomic nervous system and cardiac arrhythmias. Our purpose was not to be comprehensive, detailed, or all inclusive but to present a clinically relevant summary of some of the areas where autonomic tone may be pertinent. Clearly, most arrhythmias are not the result of a primary autonomic nervous system disorder. However, subtle and overt alterations in autonomic tone, interacting with rate, pressure, cardiac volume, contractility, and the intrinsic myocardial electrophysiologic properties likely exert a critical influence on many cardiac arrhythmias. We wish to emphasize that autonomic effects may be temporarily concealed or overwhelmed during certain states or by the administration of drugs. However, the modulating role of neural tone and neurotransmitters is almost always present, contributing significantly to the outcome of therapy.
我们力图对自主神经系统与心律失常之间的相互作用进行全面且动态的概述。我们的目的并非详尽无遗、包罗万象，而是对自主神经张力可能相关的一些领域给出具有临床相关性的总结。显然，大多数心律失常并非原发性自主神经系统疾病所致。然而，自主神经张力的细微及明显改变，与心率、血压、心脏容量、收缩力以及心肌内在电生理特性相互作用，可能对许多心律失常产生关键影响。我们希望强调，在某些状态下或通过药物给药，自主神经效应可能会暂时被掩盖或压倒。然而，神经张力和神经递质的调节作用几乎始终存在，对治疗结果有重大影响。
