Equilibrium adsorption of human serum albumin and human fibrinogen on hydrophobic and hydrophilic surfaces.

The adsorption of human serum albumin and human fibrinogen on flat surfaces was quantitatively determined by measuring the decrease in UV absorption in the adsorption solution. The applicability of the method is discussed for hydrophilic and hydrophobic materials. The values of equilibrium adsorption are presented--albumin on polyethylene, and fibrinogen on polyethylene, carbon, poly(2-hydroxyethyl methacrylate), and cellophane.