组胺在分泌性中耳炎中的作用。

The role of histamine in secretory otitis media.

作者信息

Berger G, Hawke M, Proops D W, Ranadive N S

出版信息

J Otolaryngol. 1984 Jun;13(3):172-4.

Abstract

Secretory otitis media is the most common cause of hearing loss in children. Although allergy has been suggested as a possible cause, its role as an etiologic factor in the formation of secretory otitis media is controversial. The presence of histamine in most middle ear effusions is thought to be generated from inflammatory and not allergic provocation. This potent mediator of inflammation may contribute to the chronicity of secretory otitis media.

摘要

分泌性中耳炎是儿童听力损失最常见的原因。尽管过敏被认为是一个可能的病因，但其作为分泌性中耳炎形成的致病因素的作用仍存在争议。大多数中耳积液中组胺的存在被认为是由炎症而非过敏刺激产生的。这种强大的炎症介质可能导致分泌性中耳炎的慢性化。