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[哮喘发作时呼吸、血流动力学及酸碱平衡参数的预后价值]

[Prognostic value, at the onset of an asthma attack, of respiratory, hemodynamic, and acid-base equilibrium parameters].

作者信息

Mignot P, Charbonneau P, Brun J, Bazin C, Leménager J

出版信息

Rev Pneumol Clin. 1984;40(4):227-31.

PMID:6545463
Abstract

Sudden death is still a common complication of acute asthma. The authors analysed statistically the prognostic value of the respiratory rate (RR), the heart rate (HR), blood gases, systolic blood pressure (BP syst), and diastolic pressure (BP diast) and the amplitude of the P wave in lead II on the ECG, recorded at the beginning of the asthma attack. This retrospective study concerns two groups of patients distinguished on the basis of the severity of the attack (group I: simple retrospective study concerns two groups of patients distinguished on the basis of the severity of the attack (group I: simple attack; group II; status asthmaticus). A HR greater than 24 per minute, a P wave greater than or equal to 2.5 mm or a PaCO2 greater than or equal to 6.3 kPa (47.25 mmHg) are three highly sensitive and specific criteria of the evolution of the asthma attack towards a more severe form (status asthmaticus). Patients who present one or more of these parameters should be monitored in a respiratory intensive care unit in order to prevent avoidable sudden death.

摘要

猝死仍是急性哮喘的常见并发症。作者对哮喘发作开始时记录的呼吸频率(RR)、心率(HR)、血气、收缩压(BP syst)、舒张压(BP diast)以及心电图II导联P波振幅的预后价值进行了统计学分析。这项回顾性研究涉及两组根据发作严重程度区分的患者(第一组:轻度发作;第二组:哮喘持续状态)。每分钟心率大于24次、P波大于或等于2.5毫米或动脉血二氧化碳分压(PaCO2)大于或等于6.3千帕(47.25毫米汞柱)是哮喘发作向更严重形式(哮喘持续状态)发展的三个高度敏感且特异的标准。出现这些参数中一项或多项的患者应在呼吸重症监护病房进行监测,以预防可避免的猝死。

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