Sato K, Kamata R
Radiat Med. 1984 Jan-Mar;2(1):61-70.
A study was carried out with a Rion TR-03 type electro-gustometer for subjective and quantitative expression of the degree of taste deficiency due to radiation therapy and the effects of treatment. The changes of the electro-gustometric threshold due to irradiation were examined in patients who were divided into three groups: those receiving irradiation of the whole oral cavity, those receiving irradiation of the posterior tongue and the soft palate and those receiving irradiation of the gustatory nervous system. In the group receiving irradiation of the whole oral cavity, the threshold showed a tendency to increase when receiving 10 Gy/5 days, and the threshold became unmeasurable when more than 40 Gy/26 days was given. In the group receiving irradiation of the posterior tongue and the soft palate, almost no change of the threshold in the anterior was observed in spite of increasing irradiation doses. In the group receiving irradiation of the gustatory nervous system, the threshold in the intact hemicephalus did not changed even after irradiation, but a change was found on the pathological side. Based on these results, the authors originated a complication scoring system and a treatment scoring system both of which are divided into five stages. An electro-gustometric examination is used in order to provide effective treatment with a preserving function something which has been strongly desired for radiation therapy of cancer.
使用理音TR - 03型电味觉计进行了一项研究，以主观定量表达放射治疗导致的味觉减退程度及治疗效果。将患者分为三组，研究了照射导致的电味觉阈值变化：全口腔照射组、舌后部和软腭照射组以及味觉神经系统照射组。在全口腔照射组中，当接受10 Gy/5天照射时，阈值有升高趋势，当给予超过40 Gy/26天照射时，阈值变得无法测量。在舌后部和软腭照射组中，尽管照射剂量增加，但前部阈值几乎没有变化。在味觉神经系统照射组中，未照射侧的阈值即使在照射后也没有变化，但在病变侧发现了变化。基于这些结果，作者制定了一个并发症评分系统和一个治疗评分系统，两者均分为五个阶段。进行电味觉检查是为了在保留功能的情况下提供有效的治疗，这是癌症放射治疗一直强烈期望的。
