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[不育婚姻中精子的同种及自身抗体]

[Iso and autoantibodies to spermatozoa in sterile marriages].

作者信息

Mettler L

出版信息

Zentralbl Gynakol. 1978;100(3):160-6.

PMID:654651
Abstract

Our clinical catamnestic studies on cases of sterility with a proven sensitization against spermatozoa revealed a statistically significant decrease of pregnancies only in patients with positive spermantibody tests over a period longer than 3 years. A direct spermimunological etiology of sterility can not yet be derived. In the investigated 759 cases a sensitization against spermatozoa was detected in 93 cases. In 11 patients the spermantibodies proved to be positive longer than 3 years. Washed spermatozoa were used as antigen in the applied test methods. It may very well be possible, that the results point in a different direction once we are applying a particular fertility diminishing spermatozoa antigen.

摘要

我们对已证实对精子致敏的不育病例进行的临床随访研究表明,只有精子抗体检测呈阳性超过3年的患者,其妊娠率才会出现具有统计学意义的下降。不育的直接精子免疫病因尚未明确。在调查的759例病例中,93例检测到对精子致敏。11例患者的精子抗体在3年以上呈阳性。在所应用的检测方法中,使用洗涤过的精子作为抗原。一旦我们应用一种特定的可降低生育能力的精子抗原,结果很可能会指向不同的方向。

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