Studer H, König M P
Schweiz Med Wochenschr. 1984 Mar 17;114(11):361-4.
Since the introduction of precise and easily accessible methods of measuring the level of T4 and T3 in serum, the use of isotopes to assess thyroid function can no longer be advocated. Moreover, the recent growth in knowledge concerning the pathogenesis of thyroid diseases indicates that not even scintigraphic imaging of the thyroid gland contributes substantially to therapeutic decisions in routine situations such as Graves' disease and most euthyroid and hyperthyroid nodular goiters. The use of isotopes in clinical thyroidology should therefore be restricted to the fairly few cases where it is essential for diagnostic and therapeutic decisions, such as, for example, in planning 131I-therapy of postoperative goiter recurrences. A critical review of the indications is presented. Isotopes continue, however, to expand our knowledge of the pathogenesis of thyroid diseases in clinical research.
自从引入精确且易于获取的血清T4和T3水平测量方法后，就不再提倡使用同位素来评估甲状腺功能了。此外，最近有关甲状腺疾病发病机制的知识增长表明，即使是甲状腺闪烁成像，在格雷夫斯病以及大多数甲状腺功能正常和甲状腺功能亢进的结节性甲状腺肿等常规情况下，对治疗决策也没有太大帮助。因此，临床甲状腺学中同位素的使用应仅限于对诊断和治疗决策至关重要的少数情况，例如在计划对术后甲状腺肿复发进行131I治疗时。本文对适应证进行了批判性综述。然而，同位素在临床研究中仍在不断拓展我们对甲状腺疾病发病机制的认识。
