A spirohydantoin derivative of dimethoxytetrahydronaphthalene: an experimental anticonvulsant.
作者信息
Alexander G J, Sinha B, Chatterjie N
出版信息
Neurochem Res. 1984 Apr;9(4):529-33. doi: 10.1007/BF00964379.
PMID:6547772
Abstract
A 2-spirohydantoin of 6,7-dimethoxytetrahydronaphthalene was synthesized and purified. The compound, showing structural similarities to both phenytoin and dopamine, was found to decrease spontaneous motor activity of mice and to exert a pronounced protective effect against convulsive seizures induced by pentylenetetrazol (Metrazol).
摘要
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