Austin G E, Moss T J
Arch Pathol Lab Med. 1984 Oct;108(10):811-3.
Gross and microscopic examination of equivalent segments of abdominal aortas obtained at autopsy from 39 male patients aged 10 to 30 years (mean, 20.5 years) and 37 female patients aged 9 to 30 years (mean, 20.9 years) revealed no significant difference in the prevalence of aortic pre-atherosclerotic lesions in male v female patients. The prevalence of fatty streaks and early and late fibromusculoelastic lesions did not change significantly with increasing age, suggesting that in the abdominal aorta, the majority of precursor lesions for atherosclerosis are already present by 15 years of age. These findings suggest that the reduced severity of atherosclerosis in female patients is not due to the presence of smaller numbers (or extent) of precursor lesions, but rather to slower progression of these lesions in female patients.
对39名年龄在10至30岁（平均20.5岁）的男性患者和37名年龄在9至30岁（平均20.9岁）的女性患者尸检时获取的腹主动脉等效节段进行大体和显微镜检查，结果显示男性和女性患者主动脉粥样硬化前期病变的患病率无显著差异。脂肪条纹以及早期和晚期纤维肌弹性病变的患病率并未随年龄增长而显著变化，这表明在腹主动脉中，大多数动脉粥样硬化的前期病变在15岁时就已存在。这些发现表明，女性患者动脉粥样硬化严重程度较低并非由于前期病变数量较少（或范围较小），而是由于这些病变在女性患者中的进展较慢。
