Morris R, Farmery S M, Roberts C J, Hill R G
Neurosci Lett. 1984 Jul 27;48(2):161-6. doi: 10.1016/0304-3940(84)90013-2.
The effects of microiontophoretically applied oxytocin on the firing rates of neurones in the rat caudal brainstem have been examined. Of the sample of 156 units recorded the firing rates of 33.3% were reduced and those of 21.2% were raised by microiontophoretically applied oxytocin, whilst the remainder were unaffected. The distribution of units facilitated by oxytocin tended to overlap with the distribution of oxytocin demonstrated immunocytochemically, whereas many units inhibited by oxytocin were in regions where no oxytocin was observed. Overall the excitatory but not the inhibitory effects of oxytocin could be blocked by oxytocin and vasotocin analogues with antagonist properties.
已对微量离子电泳施加催产素对大鼠尾侧脑干神经元放电频率的影响进行了研究。在记录的156个单位样本中，微量离子电泳施加催产素使33.3%的单位放电频率降低，21.2%的单位放电频率升高，其余单位则未受影响。催产素促进的单位分布倾向于与免疫细胞化学显示的催产素分布重叠，而许多受催产素抑制的单位位于未观察到催产素的区域。总体而言，具有拮抗特性的催产素和加压催产素类似物可阻断催产素的兴奋作用，但不能阻断其抑制作用。
