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The effects of microiontophoretically applied D-L, acetylcarnitine on single neurones in the rat brainstem.

作者信息

Tempesta E, Janiri L, Salera P

出版信息

Neuropharmacology. 1982 Nov;21(11):1207-10. doi: 10.1016/0028-3908(82)90182-4.

DOI:10.1016/0028-3908(82)90182-4
PMID:6129595
Abstract

D-L, Acetylcarnitine was applied microiontophoretically to neurones in the brainstem of the rat, to evaluate its possible effects. The results support the hypothesis that D-L, acetylcarnitine acts on the neuronal membrane, producing selective excitatory responses of the neurones examined. The possible role of this substance at the single neurone level is discussed in relation to the results obtained by investigating the interaction between D-L, acetylcarnitine and neurotransmitters, such as acetylcholine, gamma-aminobutyric acid (GABA), serotonin and noradrenaline.

摘要

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Action of L-acetylcarnitine on different cerebral mitochondrial populations from hippocampus and striatum during aging.
衰老过程中L-乙酰肉碱对海马体和纹状体不同脑线粒体群体的作用。
Neurochem Res. 1991 Oct;16(10):1125-32. doi: 10.1007/BF00966590.