Balázs M, Gergely R, Kostic S
Acta Hepatogastroenterol (Stuttg). 1978 Apr;25(2):111-8.
The authors report on the cases of 2 young females who had been on oral contraceptives for 2 and 6 years, respectively. During cholecystectomy, as a subsidiary finding, liver tumour was found which, histologically, proved to be focal nodular hyperplasia. On the basis of their electron-microscopic studies, they consider possible the primary role of pathological vascularization in the development of the tumour. They suggest the radical removal of the tumour and regard as inevitable for the patient the stopping of oral contraceptives, due to the recurrence or malignant transformation of the tumour.
作者报告了2例年轻女性的病例，她们分别服用口服避孕药2年和6年。在胆囊切除术期间，作为一个附属发现，发现了肝脏肿瘤，组织学检查证实为局灶性结节性增生。基于他们的电子显微镜研究，他们认为病理性血管生成在肿瘤发生中可能起主要作用。他们建议彻底切除肿瘤，并认为由于肿瘤复发或恶变，患者停用口服避孕药是不可避免的。
